Top 10 similar words or synonyms for pyrin

dhhc    0.792208

fyve    0.787802

lccl    0.781933

rhogap    0.778724

lysm    0.777612

inadl    0.768042

discoidin    0.766920

kinasedomain    0.764823

containingprotein    0.760274

rasgef    0.758165

Top 30 analogous words or synonyms for pyrin

Article Example
Pyrin domain A pyrin domain is a protein domain and a subclass of protein motif known as the death fold; it allows a pyrin domain containing protein to interact with other proteins that contain a pyrin domain. It is also known as a PYD or PAAD/DAPIN domain, and is distantly evolutionarily related to the Death domain family of protein domains. Proteins containing a pyrin domain are frequently involved in biological processes called inflammation and apoptosis. Proteins that possess a pyrin domain include intracellular microbial sensors called NOD-like receptors, and proteins associated with their function, such as PYCARD and certain fish caspases.
NALP3 This gene encodes a pyrin-like protein which contains a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with pyrin domain (PYD) of apoptosis-associated speck-like protein containing a CARD (ASC). Proteins which contain the caspase recruitment domain, CARD, have been shown to be involved in inflammation and immune response.
MEFV "MEFV" mutations lead to reduced amounts of pyrin or a malformed pyrin protein that cannot function properly. As a result, pyrin cannot perform its presumed role in controlling inflammation, leading to an inappropriate or prolonged inflammatory response. Fever and inflammation in the abdomen, chest, joints, or skin are signs of familial Mediterranean fever.
NLRP NLRP can also refer to genes that encode a series of NOD-like receptor family pyrin domains:
NLRP8 NLRP8, short for NOD-like receptor family pyrin domain containing 8, is an intracellular protein that is expressed in the ovaries, testes, and preimplantation embryos of mammals. It is also known as NALP8, NOD16, PAN4, and CLR19.2, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.