Top 10 similar words or synonyms for pyrazolopyridine

triazolopyridine    0.895158

imidazopyridazine    0.893845

imidazopyrazine    0.882699

quinolinone    0.875666

pyridopyrimidine    0.874404

quinolinones    0.872377

pyrimidinone    0.869530

pyrrolotriazine    0.864460

pyrazolopyrazine    0.864246

isoquinolinone    0.861719

Top 30 analogous words or synonyms for pyrazolopyridine

Article Example
Pyrazolopyridine The pyrazolopyridines are a group of drugs investigated as anxiolytics which act as positive allosteric modulators of the GABA receptor via the barbiturate binding site. They include the following compounds:
ICI-190,622 ICI-190,622 is an anxiolytic drug used in scientific research. It is a pyrazolopyridine derivative, related to other anxiolytic compounds such as tracazolate, and more distantly to zaleplon. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.
Tracazolate Tracazolate (ICI-136,753) is an anxiolytic drug which is used in scientific research. It is a pyrazolopyridine derivative, most closely related to pyrazolopyrimidine drugs such as zaleplon, and is one of a structurally diverse group of drugs known as the nonbenzodiazepines which act at the same receptor targets as benzodiazepines but have distinct chemical structures.
Etazolate Etazolate (SQ-20,009, EHT-0202) is an anxiolytic drug which is a pyrazolopyridine derivative and has unique pharmacological properties. It acts as a positive allosteric modulator of the GABA receptor at the barbiturate binding site, as an adenosine antagonist of the A and A subtypes, and as a phosphodiesterase inhibitor selective for the PDE4 isoform. It is currently in clinical trials for the treatment of Alzheimer's disease.
Cartazolate Cartazolate (SQ-65,396) is a drug of the pyrazolopyridine class. It acts as a GABA receptor positive allosteric modulator at the barbiturate binding site of the complex and has anxiolytic effects in animals. It is also known to act as an adenosine antagonist at the A and A subtypes and as a phosphodiesterase inhibitor. Cartazolate was tested in human clinical trials and was found to be efficacious for anxiety but was never marketed. It was developed by a team at E.R. Squibb and Sons in the 1970s.