Top 10 similar words or synonyms for progestin

progestogen    0.899055

gestagen    0.820631

levonorgestrel    0.809472

progestagen    0.776780

gestagens    0.771519

progestins    0.768463

progesterone    0.765518

oestradiol    0.763351

progestogens    0.734473

serm    0.730963

Top 30 analogous words or synonyms for progestin

Article Example
Progestin Progesterone (or sometimes dydrogesterone or hydroxyprogesterone caproate) is used for luteal support in IVF protocols, questionably for treatment of recurrent pregnancy loss, and for prevention of preterm birth in pregnant women with a history of at least one spontaneous preterm birth.
Progestin Alternatively, estranes such as noretynodrel and norethisterone are classified as first-generation while gonanes such as norgestrel and levonorgestrel are classified as second-generation, with less androgenic gonanes such as desogestrel, norgestimate, and gestodene classified as third-generation and newer progestins like drospirenone classified as fourth-generation. Yet another classification system considers there to be only first- and second-generation progestins.
Progestin In many people suffering from solid malignancy, especially gastric and pancreatic cancer, high doses of certain progestins can be employed to improve appetite and reduce wasting. In general, they are used in combination with certain other steroids such as dexamethasone. Their effects take several weeks to become apparent, but are relatively long-lived when compared to those of corticosteroids. Furthermore, they are recognized as being the only drugs to increase lean body mass. Megestrol acetate is the lead drug of this class for the management of cachexia, and medroxyprogesterone acetate is also used.
Progestin Agonists of the PR have relatively few side effects at typical dosages. Many of the side effects of progestins are due not to their progestogenic activity but rather to off-target activity, namely activity at other steroid hormone receptors like the androgen, estrogen, and glucocorticoid receptors (described below). At high dosages, progestins also have potent antigonadotropic effects via PR hyperactivation, and can produce prominent side effects related to hypogonadism in premenopausal women and in men.
Progestin The first orally active progestin, ethisterone (pregneninolone, 17α-ethynyltestosterone), the 17α-ethynyl analog of testosterone, was synthesized in 1938 from dehydroandrosterone by ethynylation, either before or after oxidation of the 3-OH group, followed by rearrangement of the 5,6 double bond to the 4,5 position. The synthesis was designed by chemists Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg and Arthur Serini at Schering AG in Berlin and was marketed in Germany in 1939 as "Proluton C" and by Schering in the U.S. in 1945 as "Pranone".