Top 10 similar words or synonyms for ectrodactyly

polydactyly    0.831442

syndactyly    0.817062

brachydactyly    0.774133

epicanthus    0.749946

dysostosis    0.749823

postaxial    0.747085

polymelia    0.732866

anophthalmia    0.730520

preaxial    0.724756

hydrocephaly    0.724420

Top 30 analogous words or synonyms for ectrodactyly

Article Example
Ectrodactyly Split hand/foot malformation (SHFM) is characterized by underdeveloped or absent central digital rays, clefts of hands and feet, and variable syndactyly of the remaining digits. SHFM is a heterogeneous condition caused by abnormalities at one of multiple loci, including SHFM1 (SHFM1 at 7q21-q22), SHFM2 (Xq26), SHFM3 (FBXW4/DACTYLIN at 10q24), SHFM4 (TP63 at 3q27), and SHFM5 (DLX1 and DLX 2 at 2q31). SHFM3 is unique in that it is caused by submicroscopic tandem chromosome duplications of FBXW4/DACTYLIN. SHFM3 is considered 'isolated' ectrodactyly and does not show a mutation of the tp63 gene.
Ectrodactyly A number of factors make the identification of the genetic defects underlying human ectrodactyly a complicated process: the limited number of families linked to each split hand/foot malformation (SHFM) locus, the large number of morphogens involved in limb development, the complex interactions between these morphogens, the involvement of modifier genes, and the presumed involvement of multiple gene or long-range regulatory elements in some cases of ectrodactyly. In the clinical setting these genetic characteristics can become problematic and making predictions of carrier status and severity of the disease impossible to predict.
Ectrodactyly Table 3: Classification for cleft hand described by Manske and Halikis
Ectrodactyly The timing of surgical interventions is debatable. Parents have to decide about their child in a very vulnerable time of their parenthood. Indications for early treatment are progressive deformities, such as syndactyly between index and thumb or transverse bones between the digital rays. Other surgical interventions are less urgent and can wait for 1 or 2 years.
Ectrodactyly Table 4: Treatment based on the classification of Manske and Halikis