Top 10 similar words or synonyms for caax

xxcc    0.701275

pstaire    0.679610

forkhead    0.674977

dexh    0.671963

deah    0.663910

deadh    0.662334

nudix    0.659764

withthrombospondin    0.646194

cystein    0.633552

gxgxxg    0.632786

Top 30 analogous words or synonyms for caax

Article Example
FAM127A CAAX box protein 1 is a protein that in humans is encoded by the "FAM127A" gene.
RCE1 CAAX prenyl protease 2 is an enzyme that in humans is encoded by the "RCE1" gene.
Prenylation Farnesyltransferase and Geranylgeranyltransferase I are very similar proteins. They consist of two subunits, the α-subunit, which is common to both enzymes, and the β-subunit, whose sequence identity is just 25%. These enzymes recognise the CaaX box at the C-terminus of the target protein. C is the cysteine that is prenylated, a is any aliphatic amino acid, and the identity of X determines which enzyme acts on the protein. Farnesyltransferase recognizes CaaX boxes where X = M, S, Q, A, or C, whereas Geranylgeranyltransferase I recognizes CaaX boxes with X = L or E.
Ras subfamily It consists of two domains, a G domain of 166 amino acids, about 20kDa, that binds guanosine nucleotides, and a C-terminal membrane targeting region (CAAX-COOH, also known as CAAX box) which is lipid-modified by farnesyl transferase, RCE1 and ICMT.
Protein methylation Eukaryotic proteins with C-termini that end in a CAAX motif are often subjected to a series of posttranslational modifications. This CAAX-tail processing takes place in three steps. First, a prenyl lipid anchor is attached to the cysteine through a thioester linkage. Then endoproteolysis occurs to remove the last three amino acids of the protein to expose the prenylcysteine α-COOH group. Finally, the exposed prenylcysteine group is methylated. The importance of this modification can be seen in targeted disruption of the methyltransferase for mouse CAAX proteins, when isoprenylcysteine carboxyl methyltransferase, resulted in mid-gestation lethality.