Top 10 similar words or synonyms for thogotovirus

influenzavirus    0.863198

isavirus    0.853330

influenzaviruses    0.831438

thogoto    0.830259

deltavirus    0.822785

papovaviridae    0.810770

hepevirus    0.807998

hepacivirus    0.807848

avihepadnavirus    0.795099

oncovirus    0.794677

Top 30 analogous words or synonyms for thogotovirus

Article Example
Thogotovirus The genome encodes 7–9 proteins, including the trimeric RNA polymerase enzyme (PA, PB1, PB2) and the structural proteins nucleoprotein (NP), which binds the viral genome; matrix protein (M1), which lines the envelope; and an envelope glycoprotein (GP), which acts as the virus receptor.
Thogotovirus Antibodies have been found to THOV in rats and many domestic animals, including goats, sheep, donkeys, camels, cattle and buffaloes, and the virus has been isolated from the wild banded mongoose ("Mongos mungo"). It causes significant livestock disease, including a febrile illness and abortion in sheep. In artificial laboratory infections, it is highly pathogenic in hamsters and also infects mice. The virus is known to infect humans in natural settings.
Thogotovirus The Araguari virus was first isolated from a Gray four-eyed opossum ("Philander opossum") in Serra do Navio, Amapá, Brazil in 1969. Its method of transmission is unknown. In laboratory infections, it is pathogenic to mice. The virion is around 105 nm in diameter. The genome has six RNA segments. Based on partial sequence data the virus was found to be most closely related to THOV.
Thogotovirus THOV and JOSV also encode the protein M-long (ML), which counters the host's innate immunity, in particular by suppressing the production of interferon. This immune evasion is important for the virus to infect systemically in vertebrates, but is unnecessary in arthropods, which lack the interferon response. The mechanism of action of ML is completely different from the equivalent protein in influenza viruses (NS1).
Thogotovirus As orthomyxoviruses do not encode a capping enzyme, initiation of transcription involves the virus cutting the cap off the 5′-end of host mRNAs, so that the mRNA is recognised by the host translation machinery. A similar "cap snatching" process is used by other orthomyxoviruses, but a much longer host RNA sequence is cleaved along with the cap and incorporated into the viral mRNA.